Look good, at a glance.
Just get people playing it, test it thoroughly. Then simply use your core rules system, swap all the names and pics for your own/genetics and release it for sale.
This is what big companies do with licences. Once the licence expires, they release a vanilla version, royalty free.
Trying to get nink of examples…
Virgin (I think) was doing Dr Who novels in the late 80s-90s. Theyost the licence when the movie came out, so continued with new adventures featuring their companions but not Who IP.
Mantics Mars attacks buildings, it think went into genetic terrain boxes after that ended.
Heck, GW lost D&D, so wrote Warhammer to use with the figs they had made for D&D.
I believe flames of war was pitched as a 40k game??? Originally.
B5 as a Trek show, prior to DS9.
So on.
Hero quest was GW/MB. Then GW made Warhammer quest by itself, if I have that right. Actually the recent version of HQ had all the MB images and figures altered to be just different enough.
Also the resent D&D changes have 3rd party rules makers changing to different rules or what not.