The pilots' opinions are largely irrelevant as to how an aircraft fits in a concept of operations or its sustainability. They don't take into account key elements such as logistics or maintenance and procurement. Often they don't take into account tactical or strategic ramifications.
Hence General Hinote's and other USAF gemnerals comments hold much more weight IMO.
Stealth aircraft are hangar queens and have far more maintenance requirements than conventional aircraft.
E.g F-22 availability has at times been as low as 50% or less and F-35s have been 60% or lower compared to 80+% for A-10, F-15, F-16D and 70%+ for F-16C. These are peace time stats that don't take into account higher wear and tear during high tempo ops.
This is also contrary to usual logic whereby older aircraft require far more maintenance due to age related problems.
IMO the F-35 also has five major Achilles heels in a peer level war:
1. It's production is global and parts production are spread across multiple countries (albeit assembled in only three locations – US, Italy and Japan). This has already caused major issues when Turkey was removed from the program and alternative parts manufacturers had to be found which cause some production delays.
F-15 and F-16 production is contained within the USA and thus secure.
2. It's short range (a problem common to nearly all American fighters). Asia Pacific requires long range capability. Aerial refuelling tankers can be used but being large non-stealthy modified airliners (KC-135 = B717, KC-10 = DC-10, new useless KC-46 = B767) they are essentially large radar beacons and increasingly vulnerable.
RAND did a study whereby F-22s engaged with older Chinese Su-27 variants (J-11/Su-27SK). The F-22s were outnumbered but managed to defeat larger groups of Chinese aircraft. But the Chinese could swarm the tankers and shoot them down which resulted in F-22s running out of fuel and ditching in the East China Sea.
3. Speed – speed is still critical for performing interceptions. And F-35 is slower the F-15/-16/-22 Mach 1.6 compared to between Mach 2-2.5 or even F/A-18 at Mach 1.8.
Speed is also key for getting out of bad situations.
To make matters worse, F-35 can only perform supersonic speed for extremely short bursts as sustained supersonic speed can structurally damage the aircraft (literally melting it). The Navy and Marine Corp variants are especially affected by this and the Navy version may not be able to perform supersonic intercepts at all.
Then the other issue – flying at full afterburner removes stealthiness (doesn't affect F-22 because its stealthiness is far more sophisticated which also contributes to poor availability).
4. Limitations in Within Visual Range combat –
The issue with structural damage means there are extreme limitations on afterburner usage which hampers any close combat which is problematic especially as Chinese and Russian aircraft are super manoeuvrable.
So whereas the F-35 might be great at setting up hit and run ambushes, it's not really capable of rapid response nor of fighting a sustained battle.
It's not an interceptor or air dominance/superiority fighter or a dog fighter. The F-22 and F-15 do these things much better and the faster extremely manoeuvrable F-16 is a far better dog fighter (even with its development bloat) and interceptor.
5. Maintenance hog/hangar queen – it's a very complicated stealth aircraft and as such requires more maintenance than older jets. Like F-22, it's availability is poorer than 4th generation non-stealth jets.
This makes it less reliable at generating sorties.
There have been deployments where F-35 had resounding availability rates. But it turns out that it wasn't just the wing/squadron maintenance crew that was deployed but also a small army of private contractors! In essence the maintenance crew is much bigger which means more mouths to feed, house etc.
In a peer level war, that matters a lot.
The F-35 ALIS automated logistics system (parts ordering system) is a complete and utter failure and is being replaced by the Operational Data Integrated Network, or ODIN which might start coming on line in 2022 (and whether it works is anyone's guess).