For miniatures:
Other than the difference in thinning agents, I find little difference in their use. Technique for each will come with experience, and will vary from one brand to the next, regardless of if enamel or acrylic.
I have used enamels since the 1970s, and acrylics since the 1980s, and am hard pressed to find any detectable yellowing on any of my 17,000 figures.
I frequently use both types of paint on the same figure, frequently within minutes of each other, and have never, ever, ever experienced any problems with the two types of paint reacting to or with each other.
I've never really found any significant difference in mixing the types of paint, and suspect that the problems relate more to skill set, or more probably, the particular paint line quality, than the type of paint themselves.
Overall, I have found more performance issues over the years with acrylic paints than enamels, usually, issues with the acrylics being too thin or having a high degree of transparency.
Regarding drying up in the bottle, I have experienced it with both, but again, far more frequently with acrylics. probably in something close to a 5 to 1 ratio (probably due to container type, more than properties of the paint). Acrylics in a shorter time span, but both last years. I have bottles of acrylic (Polly-S) currently in use from the late 1980s, and enamels in use from the mid-1980s (Pactra and Testors ModelMaster).
I find that paint in screw cap bottles, particularly glass bottles with metal caps, last longer than any form of plastics containers, or containers with pop-caps. I never used a lot of Humbrol metal tins, but for whatever reason, they had a shorter shelf life (still measured in years), than did Testors. GW paints have consistently had the shortest shelf life of any paint brands that I've used.
Enamels have outlasted acrylics with respect to handling and wear on figures.
My clean-up process is exactly the same for both types of paint, with the exception of keeping a little screw-cap glass jar of lacquer thinner for enamels v. jar of water for acrylics. Only the brush and a rag ever come in contact with either. I'm not sure what the clean-up process is that others mention relating to solvents for the enamels. The amount of solvent that evaporates during a multi-hour painting session is probably measured in milligrams.
I wash paint from my hands with dish detergent and water, and use a scrub-brush while doing so. Enamel is harder to remove, but usually takes no more than 1-2 minutes.
Overall, I prefer enamels, because they are more resistant to wear, otherwise, I wouldn't have a preference.
I find that each paint line tends to have its own smell. The one that I dislike the most is Polly-S, but I don't notice particularly over-whelming solvent fumes from painting with enamels. I mean, even if painting for hours, I'm still probably only painting a few square inches of area with any particular paint.
Since I use my brushes with both types of paint, I've never detected any particular damage from either. Since the early 1980s, I mostly have used Windsor and Newton red handled brushes (300 series?), Currently I buy the smaller sizes for about $4.25 USD a pop. I also use other W&N brushes, as well as Grumbacher, Liquitex, and other artists brands over the years. Regardless of the stated purpose of the brushes, I've never distinguished any overwhelming difference in performance associated with hobby acrylic v. hobby enamel. Handling of the brush during cleaning, is probably a bigger issue regarding brush life, and I am brutal. My most recent 000 brush is worn, though not unserviceable after six weeks, and a little over 400 miniatures.