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"Lack of females in drug trials leads to overmedicated women" Topic


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Martin From Canada14 Aug 2020 6:06 a.m. PST

Women are more likely than men to suffer adverse side effects of medications because drug dosages have historically been based on clinical trials conducted on men, suggests new research from UC Berkeley and the University of Chicago.

Researchers analyzed data from several thousand medical journal articles and found clear evidence of a drug dose gender gap for 86 different medications approved by the Federal Drug Administration (FDA), including antidepressants, cardiovascular and anti-seizure drugs and analgesics, among others.

"When it comes to prescribing drugs, a one-size-fits-all approach, based on male-dominated clinical trials, is not working, and women are getting the short end of the stick," said study lead author Irving Zucker, a professor emeritus of psychology and of integrative biology at UC Berkeley.

picture

The underlying article: link

altfritz04 Sep 2020 7:07 a.m. PST

In a similar manner women were apparently under represented in trials of heart medication based on the biased assumption that heart disease is a male problem.

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