"Ancient genetic mutation helps explain origin of some " Topic
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Tango01 | 16 Dec 2017 12:10 p.m. PST |
…human organs. "A neutral genetic mutation -- a fluke in the evolutionary process that had no apparent biological purpose -- that appeared over 700 million years ago in biological evolution could help explain the origin of complex organs and structures in human beings and other vertebrates, according to an article published in Nature Communications by a team led by CRG group leader Manuel Irimia, university professor Jordi García-Fernāndez, of the Faculty of Biology and the Institute of Biomedicine of the University of Barcelona (IBUB), and Maria Ina Arnone (Anton Dohrn Zoological Station, Italy). Specifically, this mutation, which likely occurred very early in evolution after the separation of our group from that of sea anemones, affected a gene of the Fgfr (fibroblast growth factor receptors) family. Curiously, this genetic change triggered, millions of years later, the connection between two gene regulatory networks (those controlled by ESRP and by Fgfr), which became key for the origin of many vertebrate organs and structures (lungs, forelimbs and inner ear)…" Main page link Amicalement Armand |
Bowman | 18 Dec 2017 9:13 a.m. PST |
It is surprising to find that a single gene (ESRP), through its ancestral biological role (cell adherence and motility) has been used throughout the animal scale for very different purposes: from the immune system of an echinoderm to the lips, lungs or inner ears of humans, Another nail in the coffin of Behe's Irreducible Complexity hypothesis. |
gladue | 18 Dec 2017 9:08 p.m. PST |
Ah, there isn't room to drive another nail into that one. |
Bowman | 19 Dec 2017 5:51 a.m. PST |
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Gunfreak | 19 Dec 2017 2:55 p.m. PST |
gladue with late entry into best burns of 2017. |
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