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"Inbred Neanderthals left humans a genetic burden " Topic


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Tango0107 Jun 2016 3:25 p.m. PST

"The Neanderthal genome included harmful mutations that made the hominids around 40% less reproductively fit than modern humans, according to estimates published in the latest issue of the journal Genetics. Non-African humans inherited some of this genetic burden when they interbred with Neanderthals, though much of it has been lost over time. The results suggest that these harmful gene variants continue to reduce the fitness of some populations today. The study also has implications for management of endangered species.

"Neanderthals are fascinating to geneticists because they provide an opportunity to study what happens when two groups of humans evolve independently for a long time--and then come back together," says study leader Kelley Harris, of Stanford University. "Our results suggest that inheriting Neanderthal DNA came at a cost."

Previous studies of DNA extracted from Neanderthal remains revealed that these Eurasian hominids were much more inbred and less genetically diverse than modern humans. For thousands of years, the Neanderthal population size remained small, and mating among close relatives seems to have been common…"
Full article here
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Amicalement
Armand

Personal logo ochoin Supporting Member of TMP07 Jun 2016 3:54 p.m. PST

So non-African humans have 2-4% of Neanderthal DNA & this drop can cause major problems?

Trash article.

Coelacanth193808 Jun 2016 2:22 a.m. PST

No mention of some of the other species we were thought to have interbred with.

Roderick Robertson Fezian08 Jun 2016 11:22 a.m. PST

But think what we could have done if we weren't so burdened!

capncarp19 Jun 2016 12:56 p.m. PST

"No mention of some of the other species we were thought to have interbred with."
Sorry, we don't practice rishathra here.

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