"Indigenous Arabs are direct descendants of humans who migrated out of Africa, before others continued on to colonize Europe and Asia, according to new research from Weill Cornell Medicine in New York City and Qatar. In addition to shedding light on humanity's evolution, the conclusion highlights the importance of taking population genetics into account when researching disease and developing treatments.
The investigation, published in Genome Research, sequenced the genomes of 104 Arabian Peninsula natives and compared them with 1,092 genomes from worldwide populations. The researchers compared each pair of genomes in the sample, which allowed them to cluster research participants by genome similarity so that an evolutionary tree emerged. The genomes of indigenous Arabs resulted in a unique cluster separate from the initial African population, illustrating the formation of a distinct population. European and Asian clusters diverged after the Arab population.
These genetic groupings help disentangle the ancient path of human evolution. Scientists previously hypothesized that when humans migrated out of Africa 125,000-60,000 years ago, they passed through the Arabian Peninsula, colonized Europe and Asia, and later returned. By contrast, the current findings demonstrate humans established the indigenous Arab population first…"
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